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Relationship between changes in olfactory function and cognitive decline of elderly people -developing olfactory function test for discriminating mild cognitive impairment-
https://doi.org/10.69202/0002000293
https://doi.org/10.69202/0002000293ef8ffbe0-c952-4d29-8459-39752ea44062
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
p83-94_Akihiro KAMINO.pdf (846 KB)
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| Item type | 学位論文 / Thesis or Dissertation(1) | |||||||||
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| 公開日 | 2025-12-09 | |||||||||
| タイトル | ||||||||||
| タイトル | Relationship between changes in olfactory function and cognitive decline of elderly people -developing olfactory function test for discriminating mild cognitive impairment- | |||||||||
| 言語 | en | |||||||||
| キーワード | ||||||||||
| 言語 | en | |||||||||
| 主題Scheme | Other | |||||||||
| 主題 | olfactory function | |||||||||
| キーワード | ||||||||||
| 言語 | en | |||||||||
| 主題Scheme | Other | |||||||||
| 主題 | cognitive function | |||||||||
| キーワード | ||||||||||
| 言語 | en | |||||||||
| 主題Scheme | Other | |||||||||
| 主題 | mild cognitive impairment | |||||||||
| キーワード | ||||||||||
| 言語 | en | |||||||||
| 主題Scheme | Other | |||||||||
| 主題 | community-dwelling elderly | |||||||||
| キーワード | ||||||||||
| 言語 | en | |||||||||
| 主題Scheme | Other | |||||||||
| 主題 | Nintest | |||||||||
| 資源タイプ | ||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||
| 資源タイプ | article | |||||||||
| ID登録 | ||||||||||
| ID登録 | 10.69202/0002000293 | |||||||||
| ID登録タイプ | JaLC | |||||||||
| 著者 |
KAMINO, Akihiro
× KAMINO, Akihiro
× TAKEDA, Masatoshi
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| 出版社 | ||||||||||
| 出版者 | Osaka Kawasaki Rehabilitation University | |||||||||
| 言語 | en | |||||||||
| 抄録 | ||||||||||
| 内容記述タイプ | Abstract | |||||||||
| 内容記述 | Background: Differences between age-related and dementia-related olfactory function decline require clarification. Olfactory tests are sometimes used to screen for dementia, but it is unclear whether they can be used to screen for mild cognitive impairment. Methods: We therefore examined the use of a general olfactory test (Open Essence test, Fujifilm Wako, Osaka, Japan) and an olfaction test developed to screen for dementia (Nintest, Kobayashi Pharmaceutical Co., Ltd., Osaka, Japan) for their characteristics and suitability. We sought to elucidate the relationship between cognitive decline and olfactory decline in 110 elderly community-dwelling volunteers. We administered the olfactory function tests and questionnaires on subjective decline in olfactory function and cognitive function. Results: Just 10% of the patients were aware of olfactory functional decline. The Open Essence test results were widely distributed between 0/12 and 12/12 points, with scores centered around 8/12 and 9/12, and the percentage of correct responses for each odor stimulus was distributed between 25-52%. The odor stimulus with the lowest percentage of correct responses was fried garlic (25%). Meanwhile, 32% of subjects scored a perfect 10/10 in the Nintest, with the remaining 68% of scores evenly distributed between 0/10 and 9/10. The correct response rate for the six odor stimuli was 61-72%, with little difference in correct response rates among the stimuli. Discussion: When a score of 100 was normal and ≤89 was mild cognitive impairment with ACE-III test, neither Open Essense nor Nintest did not have sufficient sensitivity and specificity to be used as a screening test for mild cognitive impairment. However, the results suggested that the fried garlic odor stimulus in the Open Essence test could be used in addition to the six odor stimuli in the Nintest as a test for screening for mild cognitive impairment. Olfactory dysfunction can be recognized prior to the onset of dementia and specific odor stimuli may reflect the pathology of dementia. |
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| 言語 | en | |||||||||
| 学位名 | ||||||||||
| 言語 | en | |||||||||
| 学位名 | Master | |||||||||
| 学位授与機関 | ||||||||||
| 言語 | en | |||||||||
| 学位授与機関名 | Graduate School of Osaka Kawasaki Rehabilitation University | |||||||||
| 学位授与年月日 | ||||||||||
| 学位授与年月日 | 2025-03-31 | |||||||||
| 書誌情報 |
en : COGNITION ＆ REHABILITATION 巻 6, 号 1, p. 83-94, ページ数 12, 発行日 2025-12-31 |
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| 冊子名 | ||||||||||
| 収録物名 | COGNITION & REHABILITATION | |||||||||
| 言語 | en | |||||||||
| ISSN | ||||||||||
| 収録物識別子タイプ | PISSN | |||||||||
| 収録物識別子 | 2436-1097 | |||||||||
