@misc{oai:kawasakigakuen.repo.nii.ac.jp:00000368, author = {Masakazu IMAOKA and Hidetoshi NAKAO and Misa NAKAMURA and Fumie TAZAKI and Mitsumasa HIDA and Ryota IMAI and Masahisa IBUKI and Motohiro MAEBUCHI and Masatoshi TAKEDA}, month = {Mar}, note = {Soy peptide, when consumed as a functional food, has been reported to improve cognitive function. The combined effects of soy peptide intake and exercise on cognitive function have been demonstrated. This study was intended to verify this effect in community-dwelling older adults with mild cognitive impairment (MCI). In this population-based, non-blinded randomized controlled trial, 27 old adults with MCI who were independent in activities of daily living, were randomly assigned to an exercise plus nutrition program (Ex + Nt group, n = 14) or to an exercise program (Ex group, n =13). For three months, both groups received an exercise regimen once a week, but the Ex + Nt group received a soy supplement every day. Pre- and post-intervention measurements included grip strength, gait speed, skeletal muscle mass index, Mini-Mental State Examination (MMSE), Trail-making Test A, and Geriatric Depression Scale scores. The study participants were found that exercise training had an increased skeletal muscle mass index and gait speed in both groups. Those in the Ex + Nt and Ex groups showed a significant time effect on MMSE composite score (p < 0.05), with increases of 2.2 points and 0.9 points, respectively. A three-month exercise class for old adult persons with MCI was suggested to improve cognitive function, muscle mass and walking speed. It was suggested that ingestion of soy peptides could improve the MMSE composite score., ORIGINAL ARTICLE}, title = {Effect of 3-month exercise and soy peptide intake on mild cognitive impairment: semi-randomized controlled trial}, year = {2022} }