@misc{oai:kawasakigakuen.repo.nii.ac.jp:00000372,
 author = {Seigo MINAMI and Ryuji KOBAYASHI and Ken KONDO and Takahiro HORAGUCHI and Takuya ISHIMORI and Hideaki AOKI and Yoshihiro FUKUMOTO and Tomoki AOYAMA},
 month = {Dec},
 note = {Objective: This investigative study aimed to elucidate the effects of purposeful activity-based electrical stimulation therapy on brain function using functional near-infrared spectroscopy (fNIRS) of a chronic stroke survivor.
Method: The sole study participant was a female patient in her late 70s who presented with right hemiplegia with a history of putaminal hemorrhage four years prior. She participated in the purposeful activity-based electrical stimulation therapy program for three months, after which she underwent assessment of motor, and cognitive functions. Pre- and post-program intervention assessments were conducted using fNIRS, Fugl-Meyer assessment, motor activity log, goal attainment scaling-light, and mini-mental state examination.
Results: fNIRS results confirmed significant differences in the increases in oxyhemoglobin concentration. For dorsiflexion movements, there was significant increase in the left-hemisphere palm region (p=0.004) and right-hemisphere finger (p=0.002)/palm regions (p=0.001); while for hand extension movements, there was significant difference in the left-hemisphere finger (p=0.018)/palm region (p=0.002) and right hemisphere palm region (p=0.001). Meanwhile, although target achievement scales had some point increases (outcome measures), they did not reach the level of effective improvements in motor functions.
Conclusion: The effects of the purposeful activity-based electrical stimulation therapy program in a chronic stroke survivor with severe upper limb paralysis suggests the influence of an ipsilateral descending pathway on the processes of brain function activation that occurred before effective motor-function improvements., ORIGINAL ARTICLE},
 title = {Effects of purposeful activity-based electrical stimulation therapy for a stroke patient with severe upper-limb paresis on cerebral hemodynamics: trial of a home-based support program},
 year = {2022}
}