@misc{oai:kawasakigakuen.repo.nii.ac.jp:00000380,
 author = {Masatoshi TAKEDA and Kayo MATSUO and Yukito UEDA and Keigo SHIRAIWA and Junya ORUI and Takanari KUBO and Koichi SHIMANO},
 month = {Dec},
 note = {Cognitive reserve is a concept proposed to explain the gap between neuropathological findings and clinical phenotypes of cognitive impairment. Education, occupation and leisure activity can be proxy-based factors affecting cognitive reserve, which are difficult to quantify objectively. Recent development of in vitro study of structural and functional evaluation has led to more precise quantification of cognitive reserve by residual-based measures. Cognitive reserve might be useful in understanding the pathogenesis of age-related cognitive decline, including neurodegenerative dementia. This paper examines the meaning of cognitive reserve and brain reserve with the aim of resolving the question of the sex difference in the incidence of Alzheimer diseas., REVIEW ARTICLE},
 title = {Cognitive reserve and sex difference in vulnerability to Alzheimer disease},
 year = {2022}
}