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内容記述 |
Background: The prevalence of sarcopenia has been suggested to have an association with cognitive decline We aimed to investigate the association between the prevalence of sarcopenia and domain-specific cognitive function and to identify specific cognitive functions that are more susceptible to changes in skeletal muscle.
Method: Enrolled in this study were 249 elderly residents of Kaizuka City, Japan (mean age: 74.2 ± 6.8 years) who voluntarily participated in a measurement of their motor and cognitive functions. Sarcopenia was assessed according to the Asian Working Group for Sarcopenia 2019 algorithm, while cognitive function was assessed using the revised Japanese version of Addenbrooke’s Cognitive Examination (ACE-R). Statistical analysis was performed by the Kruskal-Wallis test by ACE-R domain in three groups: healthy, sarcopenia and severe sarcopenia groups. The significance level was set at < 5%.
Results: In the healthy group, the scores were 17.4 ± 1.1 in attention/orientation, 21.5 ± 4.5 in memory, 10.5 ± 2.2 in verbal fluency, 23.9 ± 3.0 in language, and 15.3 ± 1.4 points in visuospatial ability. In the sarcopenia group, the scores were comparable: 17.3 ± 1.0 in attention/orientation, 22.8 ± 1.0 memory, 22.8 ± 3.3 in verbal fluency, 10.3 ± 2.4 in language, and 24.6 ± 1.2 in visuospatial ability. In the severe sarcopenia group, the scores were also comparable: 15.3 ± 1.1 for attention/orientation, 18.0 ± 0 for memory, 21.5 ± 2.8 for verbal fluency, 10.5 ± 0.9 for language overall and 15.4 ± 0.7 points for visuospatial ability.
Conclusion: No association was identified between the prevalence of sarcopenia and cognitive decline in our study subjects. |
p70-79_Shotaro TAKAMATSU.pdf (1.6 MB)
